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Opening

Cell cycle: copy, check, divide

Learning objective

Distinguish interphase, mitosis and cytokinesis, and explain why DNA is copied before division.

40 minutes · one route · start from what you show today. Point, speak, sign, draw, write or direct an adult. An adult may read or scribe your exact words. Choose one route; do not complete all three.

Arrival

LAUNCH · GCSE BIOLOGY FOUNDATION · W9 · LESSON 1 · 4 MINUTES

Four clues to start

Supported · 4 questions

1. Locate

Which part of a typical body cell contains chromosomes?

Help beside the question
Read or point first. Use the cell diagram: membrane, cytoplasm, nucleus.

Answer guidance

The nucleus.

2. Prepare

What must happen to DNA before the cell divides?

Help beside the question
Read or point first. Think about giving each new cell a full set.

Answer guidance

DNA must be copied.

3. Cell number

One cell divides once. How many daughter cells form?

Help beside the question
Read or point first. Count the final outlines, not the chromosomes.

Answer guidance

Two.

4. Reason

Why does a healing cut need new cells?

Help beside the question
Read or point first. Connect replacement with repair.

Answer guidance

New cells replace damaged or lost cells.

Standard · 4 questions

1. Locate

Which part of a typical body cell contains chromosomes?

Help beside the question
Use the cell diagram: membrane, cytoplasm, nucleus.

Answer guidance

The nucleus.

2. Prepare

What must happen to DNA before the cell divides?

Help beside the question
Think about giving each new cell a full set.

Answer guidance

DNA must be copied.

3. Cell number

One cell divides once. How many daughter cells form?

Help beside the question
Count the final outlines, not the chromosomes.

Answer guidance

Two.

4. Reason

Why does a healing cut need new cells?

Help beside the question
Connect replacement with repair.

Answer guidance

New cells replace damaged or lost cells.

Stretch · 4 questions

1. Locate

Which part of a typical body cell contains chromosomes?

Help beside the question
Use the cell diagram: membrane, cytoplasm, nucleus.

Answer guidance

The nucleus.

2. Prepare

What must happen to DNA before the cell divides?

Help beside the question
Think about giving each new cell a full set.

Answer guidance

DNA must be copied.

3. Cell number

One cell divides once. How many daughter cells form?

Help beside the question
Count the final outlines, not the chromosomes.

Answer guidance

Two.

4. Reason

Why does a healing cut need new cells? Give a reason.

Help beside the question
Connect replacement with repair.

Answer guidance

New cells replace damaged or lost cells. Accept a scientifically correct reason that uses the relevant model or evidence.

Starter

LAUNCH · GCSE BIOLOGY FOUNDATION · W9 · LESSON 1 · 4 MINUTES

Choose a first idea

A cell has copied its DNA. Has it already become two cells?

Think or discuss first. No answer chosen yet.

I do

LAUNCH · GCSE BIOLOGY FOUNDATION · W9 · LESSON 1 · 5 MINUTES

Watch the model

Four-chromosome model: DNA copying in interphaseInterphase: DNA is copied4 unreplicated chromosomes4 replicated chromosomescopySymbols show DNA copies, not visible interphase chromosome shapes.

During interphase the cell grows and copies its DNA. Each replicated chromosome has two joined sister chromatids.

Worked explanation · reveal after thinking

This schematic uses four chromosomes, not the human number. A replicated X is one chromosome with two sister chromatids. After chromatids separate, each is a chromosome. DNA copying does not mean each daughter cell has twice the chromosome number. The full cycle includes interphase, mitosis and cytokinesis. Interphase chromosome symbols show DNA copies schematically; the chromosomes are not normally visibly condensed at this stage.

32-second silent captioned explainer · optional

No sound or autoplay. Use instead of part of the modelling time, not as an extra activity.

Full transcript

Prepare and copy. During interphase the cell grows and copies its DNA. Each replicated chromosome has two joined sister chromatids.

Line up. During metaphase the replicated chromosomes line up at the centre of the cell.

Separate copies. During anaphase sister chromatids separate. One copy of each chromosome moves to each end.

Divide the cell. Nuclei reform and the cytoplasm divides. Two daughter cells each receive the same chromosome set.

We do

LAUNCH · GCSE BIOLOGY FOUNDATION · W9 · LESSON 1 · 5 MINUTES

Sort using the evidence

Choose a card, then choose a group. Explain one placement using its clue.

Drag, or use Tab and Enter to select a card and its group. Pointing or adult-directed placement works too.

Before mitosis

Mitosis

Cytokinesis

Choose a card first.

Read the card clues

DNA is copied: Copying prepares identical genetic information for each daughter cell.

The cell grows: Growth happens during interphase.

Chromosomes line up: Metaphase is part of mitosis.

Chromosome copies separate: Anaphase separates the copied information.

Nuclei reform: Telophase completes nuclear division.

Cytoplasm divides: Cytokinesis forms two separate cells.

Would a small change help? · optional

Ask the lesson teacher for clearer labels, fewer cards, reading help, an adult-directed model or more thinking time. Your teacher will explain what can change, try it and check its effect. Ask privately or pass; no extra form is needed.

Group explanations · reveal after sorting

DNA is copied → Before mitosis. Copying prepares identical genetic information for each daughter cell.

The cell grows → Before mitosis. Growth happens during interphase.

Chromosomes line up → Mitosis. Metaphase is part of mitosis.

Chromosome copies separate → Mitosis. Anaphase separates the copied information.

Nuclei reform → Mitosis. Telophase completes nuclear division.

Cytoplasm divides → Cytokinesis. Cytokinesis forms two separate cells.

I do 2

LAUNCH · GCSE BIOLOGY FOUNDATION · W9 · LESSON 1 · 4 MINUTES

Work through one example

Worked example

A parent model has 2 chromosomes. Explain why it copies DNA before dividing.

Step 1

Notice the starting set: 2 chromosomes.

Step 2

Copy the DNA during interphase: each chromosome now has two sister chromatids.

Step 3

Separate one copy of each to each new nucleus.

Step 4

Each daughter receives 2 chromosomes: a complete matching set.

We do 2

LAUNCH · GCSE BIOLOGY FOUNDATION · W9 · LESSON 1 · 4 MINUTES

Build a complete cycle

Use the six evidence cards to make a timeline. Add an arrow showing where DNA is copied. Explain why “mitosis means the whole cell cycle” is inaccurate.

StageEvidence to place
InterphaseCell grows; DNA is copied
MitosisChromosomes line up and separate; nuclei reform
CytokinesisCytoplasm divides
Worked explanation · reveal after thinking

Interphase prepares the cell; mitosis divides the nucleus; cytokinesis divides the cytoplasm. The cell cycle includes all three, so mitosis alone is not the whole cycle.

Independent

LAUNCH · GCSE BIOLOGY FOUNDATION · W9 · LESSON 1 · 10 MINUTES

Show your understanding

Supported · choose one route

1. Sequence

Draw or arrange the three main parts of the cycle.

Arrange these labels: cytokinesis / interphase / mitosis. Say: first ___, then ___, finally ___.

2. Explain

Explain why copying DNA after division would be a problem.

Use this frame: DNA must be copied before ___ so that each new cell receives ___.

3. Apply

A tissue has 8 cells. Each divides once. How many cells result?

Draw eight parent circles. Put two daughter dots beside each. Count the daughter dots.

Standard · choose one route

1. Sequence

Draw or arrange the three main parts of the cycle.

Use the three group labels.

2. Explain

Explain why copying DNA after division would be a problem.

Consider what each new cell needs at division.

3. Apply

A tissue has 8 cells. Each divides once. How many cells result?

Each parent cell makes two cells.

Stretch · choose one route

1. Sequence

Draw or arrange the three main parts of the cycle.

Use the three group labels.

2. Explain

Explain why copying DNA after division would be a problem.

Consider what each new cell needs at division.

3. Critique

“An X-shaped chromosome means the chromosome number has doubled.” Correct this.

Distinguish one chromosome from two joined chromatids.

Exit

LAUNCH · GCSE BIOLOGY FOUNDATION · W9 · LESSON 1 · 4 MINUTES

Two small checks

Supported · 2 questions

1. Order

Put these in order: mitosis / DNA copying / cytokinesis.

Help beside the question
Point or arrange first. Use: first ___, then ___, finally ___. Copy first; divide the cytoplasm last.

Answer guidance

DNA copying in interphase → mitosis → cytokinesis.

2. Explain

Why is DNA copied before mitosis?

Help beside the question
Use: my answer is ___ because ___. Point to a model or card first. Each new nucleus needs…

Answer guidance

So each daughter nucleus can receive a complete, identical chromosome set.

Standard · 2 questions

1. Order

Put these in order: mitosis / DNA copying / cytokinesis.

Help beside the question
Copy first; divide the cytoplasm last.

Answer guidance

DNA copying in interphase → mitosis → cytokinesis.

2. Explain

Why is DNA copied before mitosis?

Help beside the question
Each new nucleus needs…

Answer guidance

So each daughter nucleus can receive a complete, identical chromosome set.

Stretch · 2 questions

1. Order

Put these in order: mitosis / DNA copying / cytokinesis.

Help beside the question
Copy first; divide the cytoplasm last.

Answer guidance

DNA copying in interphase → mitosis → cytokinesis.

2. Critique

“An X-shaped chromosome means the chromosome number has doubled.” Correct this.

Help beside the question
Distinguish one chromosome from two joined chromatids.

Answer guidance

A replicated X is one chromosome with two joined sister chromatids. The amount of DNA has doubled, but the chromosome count has not doubled at this point.

Keep one useful science explanation. No additional participation record is required.

Use your book OR one ticket. Show your explanation with the supplied evidence. Say it, write it, draw it, sign it, choose it or show it; an adult can scribe it.

Plan: investigate how pH affects amylase acting on starch. Iodine turns blue-black when starch is detected; it remains orange-brown when starch is not detected. Today is preparation for the later investigation; no reaction results have been collected.

1. Order

Put these in order: mitosis / DNA copying / cytokinesis.

Help beside the question
Copy first; divide the cytoplasm last.

2. Explain

Why is DNA copied before mitosis?

Help beside the question
Each new nucleus needs…

Choose a route. Think first, then check the answers together.

1. Locate

Which part of a typical body cell contains chromosomes?

Help beside the question
Use the cell diagram: membrane, cytoplasm, nucleus.

2. Prepare

What must happen to DNA before the cell divides?

Help beside the question
Think about giving each new cell a full set.

3. Cell number

One cell divides once. How many daughter cells form?

Help beside the question
Count the final outlines, not the chromosomes.

4. Reason

Why does a healing cut need new cells?

Help beside the question
Connect replacement with repair.

Pause

Take a quiet pause.

You can look away from the screen. Come back when you are ready.

The lesson and your work are still here. Close this box to return.

Cold Call

Give thinking time. Invite a response by voice, pointing or showing work. A pupil can pass; check in privately when useful.

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Staff and files

Open this week’s resources

Knowledge organiser

MADE BY MATT / LAUNCH SCIENCE

Knowledge organiser

LAUNCH · W9 · Lesson 1 · Shared resource

Learning objective

Distinguish interphase, mitosis and cytokinesis, and explain why DNA is copied before division.

Four-chromosome model: DNA copying in interphaseInterphase: DNA is copied4 unreplicated chromosomes4 replicated chromosomescopySymbols show DNA copies, not visible interphase chromosome shapes.

Key words

Cell cycle — Growth, DNA copying and cell division.

Interphase — The cell grows and copies its DNA before mitosis.

Chromosome — A long DNA molecule packaged with proteins.

Mitosis — Division of the nucleus into two genetically identical nuclei.

Cytokinesis — Division of the cytoplasm to form two cells.

Diploid — Two sets of chromosomes, one set from each parent.

Remember

• DNA is copied before mitosis, during interphase.

• Prophase → metaphase → anaphase → telophase describes mitosis.

• Cytokinesis produces separate daughter cells.

• Mitosis supports growth, repair and asexual reproduction.

Success looks like

• Order interphase, mitosis and cytokinesis.

• Locate DNA copying before mitosis.

• Explain how each daughter gets a complete set.

W9_L1 · Pupil resource · unmarked

Word help

Cell cycle
Growth, DNA copying and cell division.
Interphase
The cell grows and copies its DNA before mitosis.
Chromosome
A long DNA molecule packaged with proteins.
Mitosis
Division of the nucleus into two genetically identical nuclei.
Cytokinesis
Division of the cytoplasm to form two cells.
Diploid
Two sets of chromosomes, one set from each parent.

TA Brief

Current stage

Current stage:

Preparation and safety

No biological samples are needed. Use cards, diagrams or an adult-directed model. Do not require cutting, standing, personal disclosure or physical contact.

Scientific care

This schematic uses four chromosomes, not the human number. A replicated X is one chromosome with two sister chromatids. After chromatids separate, each is a chromosome. DNA copying does not mean each daughter cell has twice the chromosome number. The full cycle includes interphase, mitosis and cytokinesis. Interphase chromosome symbols show DNA copies schematically; the chromosomes are not normally visibly condensed at this stage.

Responsive feedback

During We do, the lesson teacher is the named audience. Offer one optional request: clearer labels, fewer cards, reading help, adult-directed handling or more thinking time. Explain what can change, try it and check its effect. Passing or asking privately is valid. No compulsory form or written conversion of speech. Do not infer school marking codes from clicks, saved answers or a completed box.

Sources

Original Made by Matt lesson

Pearson Edexcel GCSE Biology 1BI0 specification, Issue 4 (March 2024)

Checked 16 September 2026. A local rebuilt review edition; the live website and repositories are unchanged.

Made by Matt